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BBC R4 - Frontiers 3

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	Status:	This torrent has NOT been verified.
Category:	eBooks
Infohash	96deda0555fbef41c554de682ff32ec8e5ee69e8
Size:	129.1 MB in 7 files
Release Date(s):	Torrent Release: 21-11-2023 by user
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BBC R4 - Five biology related documentaries

BBC R4 - Cilia

Broadcast November 16, 2005

BBC Blurb

In 1898 KW Zimmermann reported in a German microscopy journal

seeing fine hair-like structures on the surface of the cells

which form the tubes in kidneys. These are the cilia that

protrude from the surface of many types of cell.

Most cilia beat in a waving chorus, but on many cells - one in

particular (the primary cilium) - stays firm, poking out into its

surroundings without moving. For almost a century its purpose

was unknown, and it was thought that it was probably a vestige of

cell evolution - no longer of any consequence to human function.

But the last ten years of research has changed that. In this week's

Frontiers, Peter Evans looks at these microscopic attachments that

have suddenly taken centre stage.

The cilia seem to perform a sensory role for individual cells, tasting

the wind and moving accordingly. Defects in cilia therefore cause the

cells to do strange things. And cilia malfunction is being linked to

some human diseases from Polycystic Kidney Disease to situs inversus.

It seems a revolution in Medicine might be taking place. In the same way

doctors now talk of 'metabolic diseases' or 'genetic diseases', they may

soon start talking about 'cilia diseases'.

____________________________

BBC R4 - Stem Cells

Broadcast June 29, 2009

BBC Blurb

Sue Broom catches up on progress in stem cell research. She talks

to leading scientists in the field and finds out when treatments and

cures from our own bodies could become a realistic prospect.

Stem cells have long held the promise to cure diseases such as heart

disease, Parkinson's, Alzheimer's, sickle cell anaemia and type 1

diabetes, as well as repair damaged tissue from injury such as spinal

cord damage. But are they ready to be tried in humans?

__________________________

BBC R4 - Longevity

Broadcast May 9, 2007

BBC Blurb

Peter Evans discusses new research into the study of ageing and longevity

which could have profound implications for human life and health.

Researchers have shown that simple genes control ageing in organisms like

fruit flies and nematode worms. They can be switched on or off to increase

their lifespan by as much as six times. Similar genes are also found in humans.

Ageing is the biggest risk factor for many major diseases: cancer, heart

disease, Alzheimer’s and neurodegeneration. Could it be that instead of being

separate diseases, they are all manifestations of a single ageing process

controlled by our genes?

Peter Evans hears from the researchers who are unlocking the genetic routes

to ageing to develop drugs which can mimic their life extending properties or

block their disease causing affects.

These drugs they hope in the future will prevent some of the biggest killers

of the Western World and could even extend human lifespan by as much as ten

or twenty years.

____________________________

BBC R4 - The New Antibiotics

Wednesday 10 May 2006

BBC Blurb

In 1945 the father of antibiotics Alexander Fleming predicted

that microbes could become 'educated' to resist penicillin,

eventually making antibiotics useless against disease.

Now, with growing fears about the spread of drug-resistant

infectious diseases such as MRSA, Fleming is being proved right.

In this episode of Frontiers, Peter Evans hears from scientists

looking for new ways to defeat the super-bugs. The most recent

figures suggest that in one year 5000 people died from hospital

infections such as MRSA in one year.

In the past, science has fought off this bacterial counter-attack

by inventing new anti-microbial compounds and ensuring they are

prescribed judiciously. But today, we live in an era when virtually

no new antibiotics are in development, and even the strongest ones

we have aren't 100% effective against these microbes.

The most striking feature of many bacteria is the ability of individual

bacterium to communicate with one another and reach a "decision".

This is known as quorum sensing.

Now scientists are trying to unravel the secrets of quorum sensing in

the hope that they can learn how to block the communication between

bacteria that drives its ability to cause disease.

However, a new strain of MRSA which first surfaced in the United States

is making its way to our shores and not only is it more potent and more

resistant to existing antibiotics, it's acquired not in hospitals but

within the community. More worryingly, otherwise healthy young athlete

are as susceptible to infection as the sick and vulnerable.

Doctors at the University of California have discovered that this bacteria,

known as USA 300, has evolved over time, importing genes from elsewhere

and becoming much more virulent. By sequencing the genes, scientists hope

to develop an anti-bacterial drug to fight it.

However, treatments based on gene sequencing and quorum sensing are some

way in the future. While campaigns to make hospitals cleaner are showing

some results, some doctors feel that a more intensive effort is needed now

to develop powerful new drugs to beat MRSA and its successors.

______________________

BBC R4 - Bioprecipitation

Broadcast June 15, 2009

BBC Blurb

Richard Hollingham investigates if bacteria in the atmosphere can influence

the weather and meets some of the scientists who are working in what has been

called 'bioprecipitation'.

He talks to David Sands from Montana University, who coined the term, and

visits labs in Avignon and London where researchers are trying to understand

more about the impact of bacterial particles on our weather. If the complexities

of bioprecipitation can be unravelled, it might be possible to turn the process

to our advantage and use these extraordinary bacteria to encourage rainfall

in drought-affected regions of the world.

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FILE LIST

Filename		Size
	BBC R4 - Bioprecipitation.mp3	26.2 MB
	BBC R4 - Cilia.mp3	25.7 MB
	BBC R4 - Longevity.mp3	25.5 MB
	BBC R4 - Stem Cells.mp3	25.8 MB
	BBC R4 - The New Antibiotics.mp3	25.9 MB
	ciliaweb.jpg	9.9 KB
	Front3.txt	5.9 KB

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